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Takeshi Miura Selected Research

Carbonyl Reductase (NADPH)

9/2019Upregulation of Carbonyl Reductase 1 by Nrf2 as a Potential Therapeutic Intervention for Ischemia/ Reperfusion Injury during Liver Transplantation.
11/2017Inhibitory Effect of Fruit Juices on the Doxorubicin Metabolizing Activity of Carbonyl Reductase 1.
7/2015Synthesis of 8-hydroxy-2-iminochromene derivatives as selective and potent inhibitors of human carbonyl reductase 1.
1/2015Up-Regulation of Carbonyl Reductase 1 Renders Development of Doxorubicin Resistance in Human Gastrointestinal Cancers.
2/2013Regulation of human carbonyl reductase 1 (CBR1, SDR21C1) gene by transcription factor Nrf2.

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Takeshi Miura Research Topics

Disease

17Neoplasms (Cancer)
11/2017 - 10/2002
5Renal Cell Carcinoma (Grawitz Tumor)
08/2012 - 05/2002
4Reperfusion Injury
09/2019 - 06/2016
4Acute Kidney Injury (Acute Renal Failure)
03/2019 - 06/2016
4Prostatic Neoplasms (Prostate Cancer)
04/2013 - 01/2005
4Testicular Neoplasms (Testicular Cancer)
03/2012 - 07/2005
4Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
03/2012 - 04/2005
3Cardiotoxicity
11/2017 - 03/2015
3Carcinoma (Carcinomatosis)
07/2013 - 05/2004
3Neoplasm Metastasis (Metastasis)
08/2008 - 05/2004
2Ischemia
09/2019 - 03/2019
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 09/2017
2Necrosis
11/2018 - 06/2016
2Lymphoma (Lymphomas)
11/2017 - 01/2015
2Lung Neoplasms (Lung Cancer)
06/2015 - 01/2015
2Small Cell Carcinoma
06/2015 - 05/2004
2Hepatocellular Carcinoma (Hepatoma)
06/2015 - 02/2013
2Lymphatic Metastasis
07/2013 - 11/2007
2Testicular Germ Cell Tumor
03/2008 - 11/2005
1Osteoarthritis
10/2021
1Rheumatoid Arthritis
10/2021
1End Stage Liver Disease
09/2019
1Diabetes Complications
04/2019
1Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy
12/2018
1Breast Neoplasms (Breast Cancer)
11/2017
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
09/2017
1Stomach Neoplasms (Stomach Cancer)
01/2017
1Colonic Neoplasms (Colon Cancer)
01/2017
1Out-of-Hospital Cardiac Arrest
05/2015
1Ventricular Fibrillation
05/2015
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2015
1Heart Arrest (Cardiac Arrest)
01/2014
1Corticobasal Degeneration
08/2013
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
08/2013
1Multiple System Atrophy
08/2013
1Parkinsonian Disorders (Parkinsonism)
08/2013
1Spinal Cord Injuries (Spinal Cord Injury)
07/2013
1Urinary Bladder Neoplasms (Bladder Cancer)
07/2013
1Neurogenic Urinary Bladder (Bladder, Neurogenic)
07/2013

Drug/Important Bio-Agent (IBA)

5Carbonyl Reductase (NADPH)IBA
09/2019 - 02/2013
4EnzymesIBA
04/2019 - 05/2011
4AnthracyclinesIBA
11/2017 - 02/2013
4Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
03/2012 - 07/2005
3Yohimbine (Yocon)IBA
03/2019 - 06/2016
3Messenger RNA (mRNA)IBA
11/2018 - 02/2013
3Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
11/2018 - 12/2006
3Doxorubicin (Adriamycin)FDA LinkGeneric
11/2017 - 01/2015
3Pharmaceutical PreparationsIBA
11/2017 - 12/2010
2Aldo-Keto ReductasesIBA
04/2019 - 06/2015
2CytokinesIBA
03/2019 - 11/2018
2Cisplatin (Platino)FDA LinkGeneric
11/2018 - 01/2005
2IsatinIBA
01/2018 - 02/2013
2Norepinephrine (Noradrenaline)FDA LinkGeneric
01/2018 - 06/2016
2Short Chain Dehydrogenase-ReductasesIBA
07/2015 - 02/2013
2Docetaxel (Taxotere)FDA Link
04/2013 - 01/2005
2Oxidoreductases (Dehydrogenase)IBA
02/2013 - 08/2008
2ProstaglandinsIBA
02/2013 - 08/2008
2Biomarkers (Surrogate Marker)IBA
12/2006 - 06/2003
2Prostate-Specific Antigen (Semenogelase)IBA
05/2005 - 01/2005
2DNA (Deoxyribonucleic Acid)IBA
06/2003 - 05/2002
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
10/2021
1Analgesics (Analgesic Drugs)IBA
10/2021
1AntipyreticsIBA
10/2021
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2019
1polyolIBA
04/2019
1Aldehyde Reductase (Aldose Reductase)IBA
04/2019
1Urea (Carbamide)FDA LinkGeneric
03/2019
1JP-1302IBA
03/2019
1NitrogenIBA
03/2019
1salicylhydroxamic acid (SHAM)IBA
03/2019
1CreatinineIBA
03/2019
1RNA-Binding Proteins (RNA-Binding Protein)IBA
01/2019
1Protein AggregatesIBA
01/2019
1Lamin Type B (Lamin B)IBA
12/2018
1Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
01/2018
1Superoxides (Superoxide)IBA
01/2018
1FlavonoidsIBA
11/2017
1adriamycinolIBA
11/2017
1ProgranulinsIBA
09/2017
1Fatty Acids (Saturated Fatty Acids)IBA
01/2017
14-oxo-2-nonenalIBA
01/2017
1Oleic Acid (Oleate)IBA
01/2017
1Tumor Biomarkers (Tumor Markers)IBA
06/2015
1Tetradecanoylphorbol AcetateIBA
06/2015
1Phorbol EstersIBA
06/2015
1N 30IBA
08/2013
1ImmunosorbentsIBA
08/2013
1GhrelinIBA
08/2013
1Carcinoembryonic AntigenIBA
07/2013
1Prednisolone (Predate)FDA LinkGeneric
04/2013

Therapy/Procedure

8Therapeutics
07/2015 - 06/2003
4Nephrectomy
01/2018 - 10/2002
3Drug Therapy (Chemotherapy)
11/2005 - 11/2002
1Liver Transplantation
09/2019
1Cardiopulmonary Resuscitation (CPR)
05/2015
1Resuscitation
05/2015
1Laryngoscopes
01/2014
1Catheters
07/2013
1Cystostomy (Suprapubic Cystostomy)
07/2013
1Indwelling Catheters (Indwelling Catheter)
07/2013